Side Effects (IMDB) is one of those complicated thrillers where you are never quite sure who the real villain is. In this case you may not be sure even after the movie is over. This may be why the move, even though it is very well done, left me feeling vaguely dissatisfied.

Martin Taylor (Channing Tatum) has just been released from prison after serving a sentence for insider trading. His wife Emily (Rooney Mara) has stayed loyal to him and is eager to restart their life together. Martin has big plans to get back into the high-flying investment business, though there are worrying hints that he may be contemplating further unethical actions.

But Emily is suffering from severe depression. After a suicide attempt she ends up under the care of Dr. Jonathan Banks (Jude Law), a psychiatrist. He seems capable and well-intentioned but he is under a lot of pressure and may be willing to bend the ethical rules a bit.

After trying several standard anti-depressants Banks ends up prescribing “Ablixa”, a heavily advertised new drug. But Ablixa turns out to have side effects which in this case have tragic consequences. A tormented Dr. Banks begins an increasingly obsessive quest to find out the real cause of the tragedy.